TOP1 Antibody - N-terminal region
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Product Specifications
CAS Number
9007-83-4
Gene Name
Topoisomerase (DNA) I
Gene Aliases
TOPI
Gene ID
7150
Swiss Prot
P11387
Accession Number
NP_003277
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Target
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Partner Proteins
SUMO2; SUMO3; MDM2; UBC; SUMO1; ERG; RNF2; EED; SHFM1; CDK14; TARDBP; CDK2; HDAC9; EIF2AK2; PARP1; WHSC1; VCAM1; ITGA4; IL7R; VCP; PA2G4; NKX3-1; ESR1; RBM39; APP; UTP20; NCSTN; SUPT16H; RBM14; SF3B6; SRSF11; TPR; SNRPD1; S100A9; RPS14; HNRNPM; IK; HNRNPC
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGD
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
91kDa
Protein Length
765
NCBI Gene Symbol
TOP1
Host or Source
Rabbit
Protein Name
DNA topoisomerase 1
Gene Name URL
TOP1
Nucleotide Accession Number
NM_003286
Curated Selection
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