What is the catalog number for INPP5D Antibody - C-terminal region?

The catalog number for INPP5D Antibody - C-terminal region is ARP61033_P050-25UL.

What sizes are available for INPP5D Antibody - C-terminal region?

INPP5D Antibody - C-terminal region is available in the following size(s): 25 µL.

Is INPP5D Antibody - C-terminal region in stock?

INPP5D Antibody - C-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

INPP5D Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Inositol polyphosphate-5-phosphatase, 145kDa

Gene Aliases

SHIP, SHIP1, SHIP-1, hp51CN, SIP-145, p150Ship

Gene ID

3635

Swiss Prot

Q92835

Accession Number

NP_001017915

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5) -trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

NOTCH2NL; KRTAP10-3; KRTAP10-9; KRTAP10-7; KRT40; KHDRBS3; KRT31; DAB1; SH3KBP1; XIAP; INPPL1; LRRK1; SHC1; PTPN11; UBASH3B; CD2AP; SYK; NCK1; GRB2; CBL; UBC; ARAP1; BCR; CLYBL; MME; EPOR; TRIP10; CD300LF; DOK3; LILRB4; INPP5D; FCGR2B; GAB2; DOK2; GAB1; D

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol