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CD44 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

CD44 molecule (Indian blood group)

Gene Aliases

IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III

Gene ID

960

Swiss Prot

P16070

Accession Number

NP_001001391

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CD44

Target

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.

Partner Proteins

UBC; NF2; NEDD8; BAG1; DPP8; VHL; SRC; ANK1; ATF2; FMNL1; IQGAP1; SLC3A2; STAT3; ITGB1; FLOT2; EP300; CAV1; PRKCZ; ELAVL1; ARHGEF12; ARHGEF1; PKN1; DMP1; HMMR; TIAM1; ERBB4; VAV2; GARS; TGFBR2; TGFBR1; CD4; MMP7; SRGN; SPP1; LCK; IGFBP3; CD74; FYN; FGF2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQN

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

40kDa

Protein Length

361

NCBI Gene Symbol

CD44

Host or Source

Rabbit

Protein Name

CD44 antigen

Gene Name URL

CD44

Nucleotide Accession Number

NM_001001391

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