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EGFR Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Epidermal growth factor receptor

Gene Aliases

ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2

Gene ID

1956

Swiss Prot

P00533

Accession Number

NP_958439

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Partner Proteins

SEC61A1; UBC; CBL; ERBB4; EMD; SEC61B; DCBLD2; PML; DERL1; SOCS5; EPHA2; UBASH3B; PTPRF; EIF2AK2; MAP2K3; MAP2K2; PRKAG1; PRKAA1; PPP2R5C; PLK1; PLCG1; PFKP; PFKM; PFKL; PFKFB3; PDK1; VAV2; UCK2; UBE2G2; DNM2; CTNND1; CSNK2A1; CSNK1A1; CSK; AP3S1; AP2S1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLS

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 85%; Rabbit: 93%; Rat: 100%; Zebrafish: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

69kDa

Protein Length

628

NCBI Gene Symbol

EGFR

Host or Source

Rabbit

Protein Name

Epidermal growth factor receptor

Gene Name URL

EGFR

Nucleotide Accession Number

NM_201282

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