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HIST1H3A Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Histone cluster 1, H3a

Gene Aliases

H3/A, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3C10, H3C11, H3C12, HIST1H3A

Gene ID

8350

Swiss Prot

P68431

Accession Number

NP_003520

Reactivity

Human, Mouse, Rat, Pig, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HIST1H3A

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Partner Proteins

WHSC1; SETD1A; FBLIM1; PRDM2; PRDM6; UBC; H2AFY; H2AFX; HIST1H1B; HIST1H1E; HIST1H1C; BAZ1B; HIST1H2AG; SMARCA5; HIST1H4A; HDAC2; UHRF1; L3MBTL2; GRB2; IRF1; HDAC11; AURKC; RPS6KA3; PAK1; ATXN1; ITGA4; env; CHAF1B; ASF1B; ASF1A; AURKB; CHAF1A; EP300; LRRK

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRR

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

15kDa

Protein Length

136

NCBI Gene Symbol

HIST1H3A

Host or Source

Rabbit

Protein Name

Histone H3.1

Gene Name URL

HIST1H3A

Nucleotide Accession Number

NM_003529

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