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VEGFA Antibody - C-terminal region (ARP60980_P050)

Product Specifications

CAS Number

9007-83-4

Gene Aliases

VPF, VEGF, MVCD1

Gene ID

7422

Swiss Prot

P15692-12

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human VEGFA

Target

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

Partner Proteins

ILF3; HNRNPL; NRP1; FLT1; LYVE1; KDR; PRRG4; VPS35; U2AF1; Flt4; ELAVL1; CRYAB; HNRNPD; HGS; UBC; HSP90AA1; HSPA4; YBX3; ADAMTS1; IGFBP7; NRP2; VEGFB; SEMA3F; PGF; EPHB2; TNXB; GPC1; VTN; VEGFA; SPARC; AKT1; YBX1; CTGF; RB1; HIF1A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

35kDa

Protein Length

327

NCBI Gene Symbol

VEGFA

Host or Source

Rabbit

Gene Name URL

VEGFA

Frequently Asked Questions

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