ACTA1 antibody - N-terminal region (ARP60969_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Actin, alpha 1, skeletal muscle
Gene Aliases
ACTA, ASMA, CFTD, MPFD, NEM1, NEM2, NEM3, SHPM, CFTD1, CFTDM
Gene ID
58
Swiss Prot
P68133
Accession Number
NP_001091
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
Target
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Partner Proteins
ABL1; TRIM63; TRIM55; CEP57; AMOT; UBC; SUMO3; CDKN2A; ACTG1; BRK1; ACTBL2; NCKAP1; LRCH3; MAPK14; DSTN; NMI; UBL4A; ABRA; ABLIM2; POLR1B; RRN3; HTRA2; PTPN22; ABLIM3; BTK; CCT2; TRAF3IP1; TCP1; SNCA; PARK2; LGALS3; SHC1; GSN; CDK2; CUL1; ISG15; YWHAZ; RE
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVA
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
42kDa
Protein Length
377
NCBI Gene Symbol
ACTA1
Host or Source
Rabbit
Protein Name
Actin, alpha skeletal muscle
Gene Name URL
ACTA1
Nucleotide Accession Number
NM_001100
Curated Selection
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