CAPN1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Calpain 1, (mu/I) large subunit

Gene Aliases

CANP, muCL, CANP1, SPG76, CANPL1, muCANP

Gene ID

823

Swiss Prot

P07384

Accession Number

NP_005177

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CAPN1

Target

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

Partner Proteins

UBC; TP53; SUMO2; GINS2; BZW2; YWHAQ; SLC9A3R1; RPS6KA1; RAP1GDS1; PFAS; PEPD; MVD; EIF6; HSPA9; GNS; GLS; GLA; GBP2; EIF4E; EEF2; ECHS1; CASP7; ASS1; LDHAL6B; GINS3; SMEK2; BCCIP; CNDP2; G6PD; HNRNPD; BAG3; SPTAN1; TINAGL1; PRMT5; CREG1; VIM; SLIT3; SH3B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

82kDa

Protein Length

714

NCBI Gene Symbol

CAPN1

Host or Source

Rabbit

Protein Name

Calpain-1 catalytic subunit

Gene Name URL

CAPN1

Nucleotide Accession Number

NM_005186

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