PCSK9 Antibody

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Product Specifications

CAS Number

9007-83-4

Gene Name

Proprotein convertase subtilisin/kexin type 9

Gene Aliases

FH3, PC9, FHCL3, NARC1, LDLCQ1, NARC-1, HCHOLA3

Gene ID

255738

Swiss Prot

Q8NBP7

Accession Number

NP_777596

Reactivity

Human, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP

Target

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3) .

Partner Proteins

TUBB6; UGGT1; AGK; RHOT1; DNAJC10; DNAJB11; PGRMC1; CDIPT; DNAJA2; STUB1; PDIA4; DNAJA3; SLC25A12; UBC; TRAF2; SLC25A1; RPL28; RCN1; LDLR; HSPB1; DNAJA1; SLC25A10; CLGN; BIRC2; BACE1; PCSK9

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP

Applications

IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Pig: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

74 kDa

Protein Length

692

NCBI Gene Symbol

PCSK9

Host or Source

Rabbit

Protein Name

Proprotein convertase subtilisin/kexin type 9

Gene Name URL

PCSK9

Nucleotide Accession Number

NM_174936

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