AMACR Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Alpha-methylacyl-CoA racemase
Gene Aliases
RM, RACE, CBAS4, P504S, AMACRD
Gene ID
23600
Swiss Prot
F8W9N1
Accession Number
NP_001161067
Reactivity
Human, Rat, Cow, Dog, Horse, Pig, Rabbit
Target
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Partner Proteins
UBC; PEX5
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMVEGT
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 85%; Horse: 85%; Human: 100%; Pig: 85%; Rabbit: 79%; Rat: 91%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
43kDa
Protein Length
394
NCBI Gene Symbol
AMACR
Host or Source
Rabbit
Protein Name
Alpha-methylacyl-CoA racemase Ensembl ENSP00000371517
Gene Name URL
AMACR
Nucleotide Accession Number
NM_001167595
Curated Selection
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