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GFM2 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

G elongation factor, mitochondrial 2

Gene Aliases

RRF, EFG2, RRF2, MRRF2, hEFG2, MST027, RRF2mt, EF-G2mt, MSTP027, mEF-G 2

Gene ID

84340

Swiss Prot

Q969S9

Accession Number

NP_115756

Reactivity

Human, Cow, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GFM2

Target

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.

Partner Proteins

TRIM9; BANP; VPS52; TRIM27; UBC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVE

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Horse: 86%; Human: 100%; Pig: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

86kDa

Protein Length

779

NCBI Gene Symbol

GFM2

Host or Source

Rabbit

Protein Name

Ribosome-releasing factor 2, mitochondrial

Gene Name URL

GFM2

Nucleotide Accession Number

NM_032380

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