MARCKS Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Myristoylated alanine-rich protein kinase C substrate

Gene Aliases

MACS, 80K-L, PKCSL, PRKCSL

Gene ID

4082

Swiss Prot

P29966

Accession Number

NP_002347

Reactivity

Human, Rat, Cow, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS

Target

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Partner Proteins

UBC; TUBGCP3; UBQLN2; RPA2; PRKACA; PARK2; PKN1; PRKCB; HCVgp1; ATF2; PRKCZ; HSP90AA1; HNRNPU; DFFB; DBN1; SPP1; CDK4; CDK2; CDK1; CCNE1; ELAVL1; EBNA-LP; Mapk13; TOB1; PRKCA; NMT1; CTSB; CALM3; CALM2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAA

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol