MARCKS antibody - C-terminal region (ARP60325_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Myristoylated alanine-rich protein kinase C substrate

Gene Aliases

MACS, 80K-L, PKCSL, PRKCSL

Gene ID

4082

Swiss Prot

P29966

Accession Number

NP_002347

Reactivity

Human, Rat, Cow, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS

Target

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Partner Proteins

UBC; TUBGCP3; UBQLN2; RPA2; PRKACA; PARK2; PKN1; PRKCB; HCVgp1; ATF2; PRKCZ; HSP90AA1; HNRNPU; DFFB; DBN1; SPP1; CDK4; CDK2; CDK1; CCNE1; ELAVL1; EBNA-LP; Mapk13; TOB1; PRKCA; NMT1; CTSB; CALM3; CALM2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAA

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Human: 100%; Pig: 79%; Rabbit: 86%; Rat: 77%; Yeast: 80%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

31kDa

Protein Length

332

NCBI Gene Symbol

MARCKS

Host or Source

Rabbit

Protein Name

Myristoylated alanine-rich C-kinase substrate

Gene Name URL

MARCKS

Nucleotide Accession Number

NM_002356

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