LAMTOR3 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Aliases

MP1, MAPBP, MAPKSP1, PRO0633, MAP2K1IP1, Ragulator3

Gene ID

8649

Swiss Prot

Q9UHA4

Accession Number

NP_068805

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human LAMTOR3

Target

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.

Partner Proteins

NIF3L1; LAMTOR2; IBTK; MBD2; BHMT; PEF1; C19orf70; MRPL43; PRR3; LPCAT1; MRPS9; MRPS35; MRPL47; TOMM22; DDX28; TSR1; RNMTL1; LAMTOR1; NDUFB11; TMCO1; MRPL39; PTRH2; RAB14; MRPL51; MRPL22; UQCRQ; PUF60; RAB31; TOMM40; MSLN; TOMM70A; NUPL1; SPCS2; PICALM; V

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol