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MAP4 antibody - N-terminal region (ARP60314_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Microtubule-associated protein 4

Gene Aliases

DKFZp779A1753, MGC8617

Gene ID

4134

Swiss Prot

P27816

Accession Number

NP_002366

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4

Target

MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU) . This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.

Partner Proteins

UBC; LGR4; RPA3; RPA2; RPA1; LSM8; WDHD1; HNRNPR; PDCD6; PPP4R1; MTA2; POLR2C; POLR2A; IARS; HNRNPF; EIF2S1; CSTF2; COG7; TARDBP; BAG3; ERBB2IP; SNTA1; LDLR; IL7R; FN1; TRAF3IP1; RPS20; GRK5; EPS15; AP2M1; USP21; CUL4A; POT1; ISG15; TERF1; SIRT7; SH3KBP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPK

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

121kDa

Protein Length

1152

NCBI Gene Symbol

MAP4

Host or Source

Rabbit

Protein Name

Microtubule-associated protein 4

Gene Name URL

MAP4

Nucleotide Accession Number

NM_002375

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