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MAP3K10 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Mitogen-activated protein kinase kinase kinase 10

Gene Aliases

MST, MLK2, MEKK10

Gene ID

4294

Swiss Prot

Q02779

Accession Number

NP_002437

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K10

Target

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

Partner Proteins

MAPK9; MAPK1; MAP3K10; MAPK14; GARS; COPS2; KIAA1804; ABL2; SH3RF1; CNKSR1; YWHAE; RACGAP1; KIF3A; DNM1L; KIF3B; DLG4; KIFAP3; MAP2K4; TUBB; PHB; HTT; CLTC; CDC42; CEACAM1; HGS; DNM1; KRTAP3-4P; KIF17; MAPK8IP2; MAPK8IP1; RAC1; HPCA; NEUROD1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQP

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

104kDa

Protein Length

954

NCBI Gene Symbol

MAP3K10

Host or Source

Rabbit

Protein Name

Mitogen-activated protein kinase kinase kinase 10

Gene Name URL

MAP3K10

Nucleotide Accession Number

NM_002446

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