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LTBP1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Latent transforming growth factor beta binding protein 1

Gene Aliases

MGC163161

Gene ID

4052

Swiss Prot

Q14766-5

Accession Number

NP_000618

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human LTBP1

Target

The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs) . The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms.

Partner Proteins

FBXO6; SMURF1; ATN1; CACNA1A; TGM2; LTBP1; ITGB5; IGFBP3; FN1; FBN1; FBN2; TGFB1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 83%; Horse: 86%; Human: 100%; Mouse: 83%; Rabbit: 92%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

154kDa

Protein Length

1396

NCBI Gene Symbol

LTBP1

Host or Source

Rabbit

Protein Name

Latent-transforming growth factor beta-binding protein 1

Gene Name URL

LTBP1

Nucleotide Accession Number

NM_000627

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