CD55 Antibody - middle region
Product Specifications
Gene Name
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Gene Aliases
CR, TC, DAF, CROM, CHAPLE
Gene ID
1604
Swiss Prot
P08174
Accession Number
NP_000565
Reactivity
Human, Dog, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CD55
Target
This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF) ; binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) . Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.
Partner Proteins
UBC; NDUFB7; NDUFS7; TIMM50; INF2; SYNJ2BP; PTCD3; PTRH2; MRPL4; SLC25A24; RAB31; ZMPSTE24; PICALM; SLC12A4; SLC2A1; S100A10; MPV17; MAN2A1; GNAI3; ATP6V1E1; GPLD1; CD97; CD14; LCK; FYN; CD55; CR1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
PGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 79%; Horse: 79%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
41kDa
Protein Length
381
NCBI Gene Symbol
CD55
Host or Source
Rabbit
Protein Name
Complement decay-accelerating factor
Gene Name URL
CD55
CAS Number
9007-83-4
Nucleotide Accession Number
NM_000574
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