CYP11B1 antibody - C-terminal region (ARP60140_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Cytochrome P450, family 11, subfamily B, polypeptide 1
Gene Aliases
FHI, CPN1, CYP11B, P450C11
Gene ID
1584
Swiss Prot
P15538
Accession Number
NP_000488
Reactivity
Human, Pig, Sheep, Monkey
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CYP11B1
Target
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
Partner Proteins
CYP11B2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
ARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGL
Applications
IHC, WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%; Pig: 79%; Sheep: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
58 kDa
Protein Length
503
NCBI Gene Symbol
CYP11B1
Host or Source
Rabbit
Protein Name
Cytochrome P450 11B1, mitochondrial
Gene Name URL
CYP11B1
Nucleotide Accession Number
NM_000497
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