BYSL Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Bystin like

Gene Aliases

Enp1, BYSTIN

Gene ID

705

Swiss Prot

Q13895

Accession Number

NP_004044

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human BYST

Target

Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.

Partner Proteins

ZBTB8A; KRTAP10-3; KRTAP10-5; SMN2; TRIM27; TRIM37; MID1; GOLGA2; EPS8; EMD; PHC2; AES; KRTAP10-7; CEP57L1; BEND7; FAM9B; OLIG3; MIPOL1; RALYL; KRT40; SSX2IP; MRFAP1L1; LONRF1; KRTAP4-2; C1orf94; LTV1; L3MBTL3; LZTS2; TEKT1; DOCK8; CEP44; CEP70; CCDC33; C

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RGTGEAEEEYVGPRLSRRILQQARQQQEELEAEHGTGDKPAAPRERTTRL

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol