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AP1B1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Adaptor-related protein complex 1, beta 1 subunit

Gene Aliases

ADTB1, BAM22, KIDAR, AP105A, CLAPB2

Gene ID

162

Swiss Prot

Q10567

Accession Number

NP_001118

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AP1B1

Target

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.

Partner Proteins

UBC; EGFR; RPA3; RPA2; RPA1; TRMT61A; DIABLO; INTS9; TBC1D2; TRIP10; ABCE1; PPP6R3; NTRK2; AP1G1; VCP; BARD1; AP1M1; AP1S2; AP1S1; EPS15; AP2M1; EPN1; SNAP91; CLINT1; COPS5; CUL3; SHBG; CDK2; SIRT7; SNCA; ATF7IP; KIF13A; ATM; AP1M2; PIP5K1C; BUB1B; BUB1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVAAKE

Applications

WB, IP

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

104kDa

Protein Length

949

NCBI Gene Symbol

AP1B1

Host or Source

Rabbit

Protein Name

AP-1 complex subunit beta-1

Gene Name URL

AP1B1

Nucleotide Accession Number

NM_001127

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