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AP2A1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Adaptor-related protein complex 2, alpha 1 subunit

Gene Aliases

ADTAA, CLAPA1, AP2-ALPHA

Gene ID

160

Swiss Prot

O95782

Accession Number

NP_570603

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AP2A1

Target

This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma) . The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Partner Proteins

SUMO2; SUMO3; UBC; EGFR; EPHA2; ABCB11; RPA3; RPA2; RPA1; BIN1; PIN1; GRB2; PPP6R3; RNF11; ARRB1; MMS19; SMAD9; ITGA4; FN1; DAB2; VCAM1; PICALM; AP2A2; SHC1; MYO6; GRK5; EPS15; CRK; AP2M1; ABL1; AMPH; Epn1; RALBP1; REPS2; SYNJ1; SHBG; BRCA1; ARRB2; Edc4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

105kDa

Protein Length

955

NCBI Gene Symbol

AP2A1

Host or Source

Rabbit

Protein Name

AP-2 complex subunit alpha-1

Gene Name URL

AP2A1

Nucleotide Accession Number

NM_130787

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