ADRA2A Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Aliases

ADRA2, ADRAR, ZNF32, ADRA2R, ALPHA2AAR

Gene ID

150

Swiss Prot

P08913

Accession Number

NP_000672

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ADRA2A

Target

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

Partner Proteins

GNAO1; ADRA2A; SNTA1; GNG2; GNB1; GNAI2; UCHL1; EIF2B1; YWHAZ; PRKCD; GNAI1; ADRBK1; ADRB1; PPP1R9B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 85%; Guinea Pig: 79%; Human: 100%; Mouse: 79%; Pig: 85%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

49kDa

Protein Length

450

NCBI Gene Symbol

ADRA2A

Host or Source

Rabbit

Protein Name

Alpha-2A adrenergic receptor

Gene Name URL

ADRA2A

Nucleotide Accession Number

NM_000681

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