IGSF8 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Immunoglobulin superfamily, member 8

Gene Aliases

EWI2, PGRL, CD316, EWI-2, KCT-4, CD81P3, LIR-D1

Gene ID

93185

Swiss Prot

Q969P0

Accession Number

NP_443100

Reactivity

Human, Mouse, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IGSF8

Target

IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Partner Proteins

KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; KRTAP10-4; UBC; FBXO6; HIST1H2BK; TUBB6; TUBB7P; VPS35; TUBA8; EIF3L; TUBE1; RPL26L1; YBX2; EIF3K; LSM3; PDCD4; PABPC1; IBTK; RPL36; RPL13A; SF3B3; RPL35; SUPT16H; SRSF8; PRPF8; CCT4; ANP32B; DDX17; SYNCRIP; TUB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEW

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol