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IGSF8 antibody - middle region (ARP59875_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Immunoglobulin superfamily, member 8

Gene Aliases

EWI2, PGRL, CD316, EWI-2, KCT-4, CD81P3, LIR-D1

Gene ID

93185

Swiss Prot

Q969P0

Accession Number

NP_443100

Reactivity

Human, Mouse, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IGSF8

Target

IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Partner Proteins

KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; KRTAP10-4; UBC; FBXO6; HIST1H2BK; TUBB6; TUBB7P; VPS35; TUBA8; EIF3L; TUBE1; RPL26L1; YBX2; EIF3K; LSM3; PDCD4; PABPC1; IBTK; RPL36; RPL13A; SF3B3; RPL35; SUPT16H; SRSF8; PRPF8; CCT4; ANP32B; DDX17; SYNCRIP; TUB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEW

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Guinea Pig: 83%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

65kDa

Protein Length

613

NCBI Gene Symbol

IGSF8

Host or Source

Rabbit

Protein Name

Immunoglobulin superfamily member 8

Gene Name URL

IGSF8

Nucleotide Accession Number

NM_052868

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