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IQCB1 Antibody - C-terminal region

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Product Specifications

Gene Name

IQ motif containing B1

Gene Aliases

PIQ, NPHP5, SLSN5

Gene ID

9657

Swiss Prot

Q3KS09

Accession Number

NP_001018865

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human IQCB1

Target

This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.

Partner Proteins

TUBB; KRT87P; ATP6V1G2; PRKDC; IGHG1; UBE2V1; HDAC6; ITGA11; TWF2; XPOT; NUDT3; RAB35; CPLX1; CDIPT; TUBB4B; TUBB3; BPNT1; TUBA1B; CALCOCO2; SEC16A; IQCB1; SGPL1; PEA15; DYNLL1; GEMIN2; HIRIP3; TUBA1A; YWHAB; UCHL1; UBB; TUBB2A; TUBA4A; HSP90B1; TPI1; THB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

51kDa

Protein Length

465

NCBI Gene Symbol

IQCB1

Host or Source

Rabbit

Protein Name

IQ calmodulin-binding motif-containing protein 1

Gene Name URL

IQCB1

CAS Number

9007-83-4

Nucleotide Accession Number

NM_001023571

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