MYOC Antibody - N-terminal region (ARP59771_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Myocilin, trabecular meshwork inducible glucocorticoid response
Gene Aliases
GPOA, JOAG, TIGR, GLC1A, JOAG1
Gene ID
4653
Swiss Prot
Q99972
Accession Number
NP_000252.1
Reactivity
Human, Rat, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human MYOC
Target
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR) . The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKS
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Guinea Pig: 86%; Human: 100%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
37kDa
Protein Length
344
NCBI Gene Symbol
MYOC
Host or Source
Rabbit
Protein Name
Myocilin
Gene Name URL
MYOC
Nucleotide Accession Number
NM_000261.1
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