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ARHGEF2 antibody - C-terminal region (ARP59669_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Rho/Rac guanine nucleotide exchange factor (GEF) 2

Gene Aliases

GEF, Lfc, P40, GEFH1, LFP40, GEF-H1, NEDMHM

Gene ID

9181

Swiss Prot

Q92974

Accession Number

NP_001155855

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF2

Target

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

RPP25L; UBC; CEP250; RPA3; RPA2; RPA1; PPP6C; FBXO6; ANKRD28; PPP6R1; YWHAB; MMS19; PEX14; VCP; NOTCH1; YWHAZ; MARK2; RHOA; AKT1; USP21; ELAVL1; SUMO1; MARK4; YWHAH; YWHAG; MYC; MAPK1; TAF10; CGN; YWHAE; PAK1; RAC1; RRAS2; PLCG1; WASF1; YWHAQ

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NTSPGVTANGEARTFNGSIELCRADSDSSQRDRNGNQLRSPQEEALQRLV

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

111kDa

Protein Length

986

NCBI Gene Symbol

ARHGEF2

Host or Source

Rabbit

Protein Name

Rho guanine nucleotide exchange factor 2

Gene Name URL

ARHGEF2

Nucleotide Accession Number

NM_001162383

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