ALDH5A1 antibody - middle region (ARP59587_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Aldehyde dehydrogenase 5 family, member A1

Gene Aliases

SSDH, SSADH

Gene ID

7915

Swiss Prot

P51649

Accession Number

NP_001071

Reactivity

Human, Rat, Cow, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ALDH5A1

Target

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD (+) -dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA) . In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

MAGEA11; TOMM40; VDAC1; TIAL1; SSBP1; SOD2; EBNA-LP; ABAT

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAM

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Guinea Pig: 79%; Human: 100%; Rabbit: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

57kDa

Protein Length

535

NCBI Gene Symbol

ALDH5A1

Host or Source

Rabbit

Protein Name

Succinate-semialdehyde dehydrogenase, mitochondrial

Gene Name URL

ALDH5A1

Nucleotide Accession Number

NM_001080

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