NUMB Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Numb homolog (Drosophila)

Gene Aliases

S171, C14orf41, c14_5527

Gene ID

8650

Swiss Prot

P49757-4

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human NUMB

Target

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

TP53; PRKCA; PRKCZ; PRKCE; PRKCB; UBC; SIAH1; RPL3; EGFR; NOTCH1; MDM2; APP; Trp53; Jun; EPS15; Lnx1; ITCH; GLI1; LNX2; AP2A2; PRKCH; DPYSL2; AP2A1; ITGB2; L1CAM; PRKCG; PRKCD; ITGB3; ITGB5; Eps15l1; RALBP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol