UFD1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitin recognition factor in ER associated degradation 1

Gene Aliases

UFD1L

Gene ID

7353

Swiss Prot

Q92890

Accession Number

NP_005650

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UFD1L

Target

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

Partner Proteins

HUWE1; YOD1; VCP; UBC; SHFM1; SUZ12; BTRC; EZH2; PDCD4; NPLOC4; NFKBIA; NUB1; NEDD8; CAV1; ADRB2; FAF1; TXLNA; UNC45A; VPS33B; UBE3A; UBE2N; PSMD7; SPRTN; UBXN6; GZMK; ERLIN2; ITPR1; PPHLN1; ANAPC2; TIAM2; TAF1C; TP53; SNX1; MASP1; PIK3CA; NGFR; IGHM; F13

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPERQVQHEEST

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

34kDa

Protein Length

307

NCBI Gene Symbol

UFD1

Host or Source

Rabbit

Protein Name

Ubiquitin recognition factor in ER-associated degradation protein 1

Gene Name URL

UFD1

Nucleotide Accession Number

NM_005659

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