ZRANB1 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Zinc finger, RAN-binding domain containing 1

Gene Aliases

TRABID

Gene ID

54764

Swiss Prot

Q9UGI0

Accession Number

NP_060050

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ZRANB1

Target

ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains.ZRANB1 acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. ZRANB1 may also modulate TNF-alpha signaling.

Partner Proteins

Btrc; UBC; CORO7; STRIP1; CTTNBP2; CTTNBP2NL; STRN3; STRN4; HECTD1; SLMAP; STRN; UBE2S; TRAF6; Apc; PGAM5; STRIP2; CACYBP; FGFR1OP2; MOB4; BICD2; FBXW11; KEAP1; GCC2; MAP4K4; HERC2; ALDH18A1; PPP2R1B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREW

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

81kDa

Protein Length

708

NCBI Gene Symbol

ZRANB1

Host or Source

Rabbit

Protein Name

Ubiquitin thioesterase ZRANB1

Gene Name URL

ZRANB1

Nucleotide Accession Number

NM_017580

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