What is the catalog number for USP6 Antibody - C-terminal region (ARP59335_P050)?

The catalog number for USP6 Antibody - C-terminal region (ARP59335_P050) is ARP59335_P050.

What sizes are available for USP6 Antibody - C-terminal region (ARP59335_P050)?

USP6 Antibody - C-terminal region (ARP59335_P050) is available in the following size(s): 100 µL.

Is USP6 Antibody - C-terminal region (ARP59335_P050) in stock?

USP6 Antibody - C-terminal region (ARP59335_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

USP6 Antibody - C-terminal region (ARP59335_P050)

Selected Variant

ARP59335_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitin specific peptidase 6 (Tre-2 oncogene)

Gene Aliases

HRP1, TRE2, TRE17, Tre-2, TRESMCR, USP6-short

Gene ID

9098

Swiss Prot

P35125-2

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human USP6

Target

USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoformÂ 2, but not isoformÂ 3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Partner Proteins

EXOSC8; CALM2; MDFI; APP; ATXN7L3; ANKRD44; RAB33B; MYL2; ARF6; RAC1; CDC42; UBC; USP32

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NHSEEDSTDDQREDTHIKPIYNLYAISCHSGILSGGHYITYAKNPNCKWY

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 91%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

119kDa

Protein Length

1089

NCBI Gene Symbol

USP6

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase 6

Gene Name URL