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USP1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitin specific peptidase 1

Gene Aliases

UBP

Gene ID

7398

Swiss Prot

O94782

Accession Number

NP_003359

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human USP1

Target

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.

Partner Proteins

WDR48; UBC; DTX3; TRIM46; PHF7; TRAF6; UBE2A; UNC45A; VPS36; WDR5; VPS26A; CSE1L; PHLPP1; PCNA; SUMO2; ATAD5; ID2; FANCD2; USP1; DSG1; DSC1; CALML3; ANXA2P2; ALDH16A1; CALML5; PHLPP2; TAGLN2; USP4; PKP1; MYH9; LYZ; LGALS7; KRT17; KRT4; KPNA1; JUP; HSPB1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SETSDTTGTHESDRNKESSDQTGINISGFENKISYVVQSLKEYEGKWLLF

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 86%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

88kDa

Protein Length

785

NCBI Gene Symbol

USP1

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase 1

Gene Name URL

USP1

Nucleotide Accession Number

NM_003368

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