A2M Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Alpha-2-macroglobulin

Gene Aliases

A2MD, CPAMD5, FWP007, S863-7

Gene ID

Swiss Prot

P01023

Accession Number

NP_000005

Reactivity

Human

Target

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

Partner Proteins

MAPK6; CDK7; CDK11A; HIPK1; FBXO6; CFTR; TP63; TGM2; IFIT3; DNAJB1; GCDH; FARSA; ENO2; ELAVL3; CYP2C18; CYP2C8; ATP1A1; APP; APOE; ACTB; A2M; RNF32; SWSAP1; TRAPPC5; EVI5L; EGLN2; IGSF8; PRAM1; MLST8; STAMBPL1; RETN; FBXL12; ECSIT; FIS1; EXOSC1; IFIT5; NC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKV

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol