A2M antibody - N-terminal region (ARP59224_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Alpha-2-macroglobulin
Gene Aliases
A2MD, CPAMD5, FWP007, S863-7
Gene ID
2
Swiss Prot
P01023
Accession Number
NP_000005
Reactivity
Human
Target
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Partner Proteins
MAPK6; CDK7; CDK11A; HIPK1; FBXO6; CFTR; TP63; TGM2; IFIT3; DNAJB1; GCDH; FARSA; ENO2; ELAVL3; CYP2C18; CYP2C8; ATP1A1; APP; APOE; ACTB; A2M; RNF32; SWSAP1; TRAPPC5; EVI5L; EGLN2; IGSF8; PRAM1; MLST8; STAMBPL1; RETN; FBXL12; ECSIT; FIS1; EXOSC1; IFIT5; NC
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
PVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKV
Applications
WB, IHC
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
161kDa
Protein Length
1474
NCBI Gene Symbol
A2M
Host or Source
Rabbit
Protein Name
Alpha-2-macroglobulin
Gene Name URL
A2M
Nucleotide Accession Number
NM_000014
Curated Selection
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