CSTB Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cystatin B (stefin B)

Gene Aliases

PME, ULD, CST6, EPM1, STFB, CPI-B, EPM1A

Gene ID

1476

Swiss Prot

P04080

Accession Number

NP_000091

Reactivity

Human, Rat, Cow, Horse, Pig, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CSTB

Target

CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.

Partner Proteins

UBC; SARNP; DPP7; BAG3; CFTR; ECT2; SEC24A; NUDC; MAT2A; FLNB; DCUN1D1; CUL3; RAD21; SPRY2; CTSL; CTSD; CTSH; CTSB; CST3; VHL

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRV

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Horse: 93%; Human: 100%; Pig: 92%; Rat: 75%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

11kDa

Protein Length

NCBI Gene Symbol

CSTB

Host or Source

Rabbit

Protein Name

Cystatin-B

Gene Name URL

CSTB

Nucleotide Accession Number

NM_000100

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

HY-W718292 1 Each

1,1,2-Trimethyl-1H-benz[e]indole-d6

Ask

View Details

RA21717-01 50 µL

AGS3 Polyclonal Antibody

Ask

View Details

RA21717-02 100 µL

AGS3 Polyclonal Antibody

Ask

View Details

NBP2-99690AF594 0.1 mL

Rabbit Polyclonal SR-BI Antibody [Alexa Fluor 594]

Ask

View Details

GWB-180B0F 0.25 mL

MRP6 Antibody

Ask

View Details

145672 10 mg

Elacridar hydrochloride (GF 120918, P-gp inhibitor, (N-[4-[2- (3,4-Dihydro-6,7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride)

Ask

View Details

CSTB Antibody - N-terminal region

Product Specifications

CAS Number

Gene Name

Gene Aliases

Gene ID

Swiss Prot

Accession Number

Reactivity

Immunogen

Target

Partner Proteins

Clonality

Type

Sequence

Applications

Purification

Assay Protocol

Concentration

Homology

Format

Reconstitution

Molecular Weight

Protein Length

NCBI Gene Symbol

Host or Source

Protein Name

Gene Name URL

Nucleotide Accession Number

Explore Other Products

1,1,2-Trimethyl-1H-benz[e]indole-d6

AGS3 Polyclonal Antibody

AGS3 Polyclonal Antibody

Rabbit Polyclonal SR-BI Antibody [Alexa Fluor 594]

MRP6 Antibody

Elacridar hydrochloride (GF 120918, P-gp inhibitor, (N-[4-[2- (3,4-Dihydro-6,7-dimethoxy-­2 (1H) -isoquinolinyl) ethyl]phenyl]-9,10-dihydro-5-m­ethoxy-9-oxo-4-acridinecarboxamide hydrochloride)

Elacridar hydrochloride (GF 120918, P-gp inhibitor, (N-[4-[2- (3,4-Dihydro-6,7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride)