RORG Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

RAR related orphan receptor C

Gene Aliases

TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA

Gene ID

6097

Swiss Prot

P51449

Accession Number

NP_001001523

Reactivity

Human, Rat, Cow, Horse, Pig, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RORG

Target

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

EVI2A; NCOA6; EIF3I; CHD4; EIF4EBP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPLG

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Horse: 85%; Human: 100%; Pig: 100%; Rat: 91%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

56 kDa

Protein Length

518

NCBI Gene Symbol

RORC

Host or Source

Rabbit

Protein Name

Nuclear receptor ROR-gamma

Gene Name URL

RORG

Nucleotide Accession Number

NM_001001523.1

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