CD3E Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
CD3e molecule, epsilon (CD3-TCR complex)
Gene Aliases
T3E, TCRE, IMD18
Gene ID
916
Swiss Prot
P07766
Accession Number
NP_000724
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CD3E
Target
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Partner Proteins
UBC; CSK; ZAP70; SNTA1; PTPN22; PIK3R2; PIK3R1; LAT; LCK; CD38; CD247; CD3G; TRAT1; NCK2; UNC119; SHC1; NCK1; SYK; CD3D; NCL; CD79B; TOP2B; CD3EAP; JAK3
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QYPGSEILWQHNDKNIGGDEDDKNIGSDEDHLSLKEFSELEQSGYYVCYP
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
23kDa
Protein Length
207
NCBI Gene Symbol
CD3E
Host or Source
Rabbit
Protein Name
T-cell surface glycoprotein CD3 epsilon chain
Gene Name URL
CD3E
Nucleotide Accession Number
NM_000733
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