Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

IL7R Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 7 receptor

Gene Aliases

ILRA, CD127, IL7RA, CDW127, IL-7R-alpha

Gene ID

3575

Swiss Prot

P16871

Accession Number

NP_002176

Reactivity

Human, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IL7R

Target

The protein encoded by this gene is a receptor for interleukine 7 (IL7) . The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V (D) J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID) .

Partner Proteins

KIT; JAK3; SNRPG; SNRPD3; SNRPD2; SNRPD1; SNRPB; SNRPA; SNRNP70; SRSF3; SAFB; RPS20; RPS3; RPL31; RPL29; RPL30; RPL22; RPL18; RPL15; RPL8; RPL7; RPL6; RBM3; PURB; PURA; PTMA; PTBP1; EIF2AK2; YBX1; NONO; NCL; MAP4; RPSA; ILF3; ILF2; HNRNPU; HNRNPL; HNRNPH3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCP

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 92%; Horse: 83%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

49kDa

Protein Length

459

NCBI Gene Symbol

IL7R

Host or Source

Rabbit

Protein Name

Interleukin-7 receptor subunit alpha

Gene Name URL

IL7R

Nucleotide Accession Number

NM_002185

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Polyclonal LRRC56 Antibody [FITC]
NBP2-98195F 0.1 mL

Rabbit Polyclonal LRRC56 Antibody [FITC]

Sign In for Pricing
View Details
Recombinant Human Lamin B1 Protein - (Dry Ice)
H00004001-P01-25ug 25 µg

Recombinant Human Lamin B1 Protein - (Dry Ice)

Sign In for Pricing
View Details
CCR2 Antibody
A18722-50UG 50 µg

CCR2 Antibody

Sign In for Pricing
View Details
Lentiviral human ENSA shRNA (UAS) - Lentiviral human ENSA shRNA (UAS, iRFP) (100)
GTR15079431 1 Vial

Lentiviral human ENSA shRNA (UAS) - Lentiviral human ENSA shRNA (UAS, iRFP) (100)

Sign In for Pricing
View Details
MOB1A Protein Vector (Rat) (pPB-N-His)
PV282683 500 ng

MOB1A Protein Vector (Rat) (pPB-N-His)

Sign In for Pricing
View Details
Tortoside A
M32250-01 100 mg

Tortoside A

Sign In for Pricing
View Details