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AXL Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

AXL receptor tyrosine kinase

Gene Aliases

ARK, UFO, JTK11, Tyro7

Gene ID

558

Swiss Prot

P30530

Accession Number

NP_001690

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AXL

Target

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

RANBP9; UBC; TYRO3; FBXO25; STUB1; HSP90AA1; HSPA1A; ERRFI1; TNK2; ELAVL1; CBL; SHC3; SOCS1; PIK3R2; ADAM10; SHC1; GAS6; SRC; PTPN11; PLCG1; PIK3R1; LCK; AXL; GRB2; TENC1; PIK3R3; NCK2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QPDPKDSCSCLTAAEVHPAGRYVLCPSTTPSPAQPADRGSPAAPGQEDGA

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 85%; Pig: 86%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

98 kDa

Protein Length

885

NCBI Gene Symbol

AXL

Host or Source

Rabbit

Protein Name

Tyrosine-protein kinase receptor UFO

Gene Name URL

AXL

Nucleotide Accession Number

NM_001699

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