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CASP6 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Caspase 6, apoptosis-related cysteine peptidase

Gene Aliases

MCH2

Gene ID

839

Swiss Prot

P55212

Accession Number

NP_001217

Reactivity

Human, Mouse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CASP6

Target

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

Partner Proteins

CASP6; XIAP; CRYAB; UBC; CASP3; RB1; IKBKG; PRKAB2; SP1; COPS6; SATB1; TAB1; MAPK6; PIN1; UBE4A; NUAK1; UBE4B; CHD3; PSME3; EIF2S1; CFLAR; PPL; NEDD4; SRP72; CASP8; CASP10; TRAF1; PSEN2; SRF; VIM; PRKCZ; MAPT; LMNB1; LMNA; KRT18; HTT; TOP1; DSP; PCYT1A; T

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCY

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 82%; Pig: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

33kDa

Protein Length

293

NCBI Gene Symbol

CASP6

Host or Source

Rabbit

Protein Name

Caspase-6

Gene Name URL

CASP6

Nucleotide Accession Number

NM_001226

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