CASP6 antibody - middle region (ARP58994_P050)
Product Specifications
Gene Name
Caspase 6, apoptosis-related cysteine peptidase
Gene Aliases
MCH2
Gene ID
839
Swiss Prot
P55212
Accession Number
NP_001217
Reactivity
Human, Mouse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CASP6
Target
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Partner Proteins
CASP6; XIAP; CRYAB; UBC; CASP3; RB1; IKBKG; PRKAB2; SP1; COPS6; SATB1; TAB1; MAPK6; PIN1; UBE4A; NUAK1; UBE4B; CHD3; PSME3; EIF2S1; CFLAR; PPL; NEDD4; SRP72; CASP8; CASP10; TRAF1; PSEN2; SRF; VIM; PRKCZ; MAPT; LMNB1; LMNA; KRT18; HTT; TOP1; DSP; PCYT1A; T
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCY
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%; Mouse: 82%; Pig: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
33kDa
Protein Length
293
NCBI Gene Symbol
CASP6
Host or Source
Rabbit
Protein Name
Caspase-6
Gene Name URL
CASP6
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001226
Curated Selection
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