What is the catalog number for CASP4 antibody - middle region (ARP58990_P050)?

The catalog number for CASP4 antibody - middle region (ARP58990_P050) is ARP58990_P050.

What sizes are available for CASP4 antibody - middle region (ARP58990_P050)?

CASP4 antibody - middle region (ARP58990_P050) is available in the following size(s): 100 µL.

Is CASP4 antibody - middle region (ARP58990_P050) in stock?

CASP4 antibody - middle region (ARP58990_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

CASP4 antibody - middle region (ARP58990_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Caspase 4, apoptosis-related cysteine peptidase

Gene Aliases

TX, Mih1, ICH-2, Mih1/TX, ICEREL-II, ICE (rel) II

Gene ID

837

Swiss Prot

P49662

Accession Number

NP_001216

Reactivity

Human, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CASP4

Target

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Partner Proteins

MYH9; ELF4; APP; TRAF6; PLA2G4A; NOD1; CASP14; CASP4; APAF1; SERPINB9; CASP10; IL18; CASP3; IL1B; DSP; PSEN1; IL37; CASP8; CASP1; XIAP; MYCBPAP; SLC25A22; SRPRB; CTNNBIP1; DNAAF5; MTHFD1L; UFL1; GCN1L1; SMC2; NUP93; SMC3; SMC1A; USP9X; VDAC3; PSMB1; MSH6

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GILEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol