MYD88 Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Myeloid differentiation primary response 88
Gene Aliases
IMD68, MYD88D
Gene ID
4615
Swiss Prot
Q99836
Accession Number
NP_001166037.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MYD88
Target
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Partner Proteins
MYD88; IRAK4; IL1R1; IKBKG; SPOP; SYK; SASH1; TRAF6; SIAH2; SIAH1; PFKL; PRDX1; MDM2; MAL; SMAD3; MBIP; TLR7; TNFRSF13B; CD93; IKBKE; POLR1C; IL1RL1; FADD; USP7; TXN; BST2; SMURF1; LRRFIP2; UBC; SMAD6; IRF5; IRAK1; BTK; PELI1; STAP2; TNIP1; TRAF3; IRAK2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
NVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVG
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Horse: 79%; Human: 100%; Rabbit: 79%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
32 kDa
Protein Length
296
NCBI Gene Symbol
MYD88
Host or Source
Rabbit
Protein Name
Myeloid differentiation primary response protein MyD88
Gene Name URL
MYD88
Nucleotide Accession Number
NM_001172566.1
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