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NAGLU Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

N-acetylglucosaminidase, alpha

Gene Aliases

NAG, CMT2V, MPS3B, UFHSD, MPS-IIIB

Gene ID

4669

Swiss Prot

P54802

Accession Number

NP_000254

Reactivity

Human, Cow, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human NAGLU

Target

This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Partner Proteins

UBC; FBXO6

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKP

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 92%; Human: 100%; Pig: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

81kDa

Protein Length

743

NCBI Gene Symbol

NAGLU

Host or Source

Rabbit

Protein Name

Alpha-N-acetylglucosaminidase

Gene Name URL

NAGLU

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