What is the catalog number for PPP4C Antibody - middle region?

The catalog number for PPP4C Antibody - middle region is ARP58516_P050-25UL.

What sizes are available for PPP4C Antibody - middle region?

PPP4C Antibody - middle region is available in the following size(s): 25 µL.

Is PPP4C Antibody - middle region in stock?

PPP4C Antibody - middle region is currently made to order / not held in immediate stock. Contact us for lead time.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

PPP4C Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 4, catalytic subunit

Gene Aliases

PP4, PPX, PP-X, PP4C, PPH3, PPP4

Gene ID

5531

Swiss Prot

P60510

Accession Number

NP_002711

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PPP4C

Target

PPP4C is a protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF) -alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDC2/Cdk1 phosphorylation sites and negatively regulates CDC2/Cdk1 activity in interphase.

Partner Proteins

SUMO2; IKBKG; MAP4K1; BAG6; TCP1; UBC; CAND1; CUL3; Igbp1; TRIM28; ELAVL1; TK1; PPP2R5D; PPP2R4; PPP2R2B; PPP2R1A; EEF1A1; CCT6A; SMEK2; PPP2R2D; SMEK1; ATAD3A; PPME1; CCT5; CCT8; CCT2; CCT4; CCT7; PPP4R1; PLOD3; CCDC6; TUBA3C; CCT3; CCT6P1; GLYATL3; PPP4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKP

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol