GRB2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Growth factor receptor-bound protein 2

Gene Aliases

ASH, Grb3-3, MST084, NCKAP2, MSTP084, EGFRBP-GRB2

Gene ID

2885

Swiss Prot

P62993

Accession Number

NP_002077

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

AES; C1orf94; LNX1; LZTS2; GAREM; ARHGAP9; NIF3L1; HOMEZ; DPPA4; TP53BP2; SHC1; TRIM27; REL; EPS8; HNRNPK; ERBB4; ABI3; ZBTB7B; IKZF3; INCA1; PRR22; PNMA5; STAMBP; DDX17; CBLB; LMO2; LCP2; ABL2; ABL1; NUTM2F; WBP11; GAB2; WASL; UBC; CBL; DNM1; EGFR; ACTG1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

24kDa

Protein Length

217

NCBI Gene Symbol

GRB2

Host or Source

Rabbit

Protein Name

Growth factor receptor-bound protein 2

Gene Name URL

GRB2

Nucleotide Accession Number

NM_002086

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