CAPNS1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Calpain, small subunit 1

Gene Aliases

CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4

Gene ID

826

Swiss Prot

P04632

Accession Number

NP_001003962

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1

Target

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Partner Proteins

AGTRAP; HUWE1; NEDD1; TUBGCP2; TUBGCP3; CDC20; UBC; OGFOD1; STK26; ISOC1; DCPS; MAT2B; PROSC; FERMT2; YWHAQ; PDIA4; YWHAZ; YWHAH; YWHAG; YWHAE; PTMA; PPP1CA; PAK2; PAFAH1B1; MYO1E; MAT2A; GNAI3; GAPDH; EIF5; TBCB; ALDH7A1; ASNS; APEX1; ADRB2; PPARGC1A; VC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

29kDa

Protein Length

268

NCBI Gene Symbol

CAPNS1

Host or Source

Rabbit

Protein Name

Calpain small subunit 1

Gene Name URL

CAPNS1

Nucleotide Accession Number

NM_001003962

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