JMJD2B Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Lysine (K) -specific demethylase 4B

Gene Aliases

JMJD2B, TDRD14B

Gene ID

23030

Swiss Prot

O94953

Accession Number

NP_055830

Reactivity

Human, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human JMJD2B

Target

JMJD2 family proteins are classified into one group with JD2H and TUDOR domains and another group without JD2H or TUDOR domains. Because JMJD2C gene (also known as GASC1 gene) is amplified in esophageal squamous cell carcinoma (ESCC), JMJD2 family genes are cancer-associated genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. In addition, JMJD2D homologous genes within human genome sequences AP002383.3 and AP001264.4 were designated JMJD2E and JMJD2F, respectively. C2HC2HC2- and C5HC2-type Cys (His) clusters were identified as the region conserved among JMJD2A (1064 aa), JMJD2B (1096 aa), and JMJD2C (1056 aa) proteins. JMJD2A, JMJD2B and JMJD2C consist of JmjN, JmjC, JD2H, and two TUDOR domains.

Partner Proteins

UBC; H3F3C; HSP90B1; HSP90AA2P; SMU1; KMT2C; WDR5; ASH2L; KMT2D; RBBP5; HSPA4; HNRNPU; ESR1; MED10

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

CAICTLFYPYCQALQTEKEAPIASLGEGCPATLPSKSRQKTRPLIPEMCF

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 92%; Horse: 92%; Human: 100%; Pig: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

122kDa

Protein Length

1096

NCBI Gene Symbol

KDM4B

Host or Source

Rabbit

Protein Name

Lysine-specific demethylase 4B

Gene Name URL

KDM4B

Nucleotide Accession Number

NM_015015

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RC214312L3V 200 µL

SARG (C1orf116) (NM_001083924) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

MBS7080860 Inquire

Recombinant Dictyostelium discoideum Putative uncharacterized transmembrane protein DDB_G0286493 (DDB_G0286493), partial

Ask

View Details

NBP2-73165APC 0.1 mL

Mouse Monoclonal Osteopontin/OPN Antibody (OTI5E4) [Allophycocyanin]

Ask

View Details

6120P-100 12/pk

FUNNEL, 100 MM, PP

Ask

View Details

sc-227281 1 g

Azidotributyltin (IV)

Ask

View Details

MBS1111204-01 0.02 mg (E-Coli)

Recombinant Staphylococcus aureus Enolase (eno)

Ask

View Details